Molecularly Imprinted Polymers for 5-Fluorouracil Release in Biological Fluids
نویسندگان
چکیده
منابع مشابه
Molecularly imprinted polymers for 5-fluorouracil release in biological fluids.
The aim of this work was to investigate the possibility of employing Molecularly Imprinted Polymers (MIPs) as a controlled release device for 5-fluorouracil (5-FU) in biological fluids, especially gastrointestinal ones, compared to Non Imprinted Polymers (NIPs). MIPs were synthesized using methacrylic acid (MAA) as functional monomer and ethylene glycol dimethacrylate (EGDMA) as crosslinking ag...
متن کاملSurface Molecularly Imprinted Polymer of Chitosan Grafted Poly(methyl methacrylate) for 5-Fluorouracil and Controlled Release
The molecular surface imprinted graft copolymer of chitosan with methyl methacrylate (MIP-CS-g-PMMA) were prepared by free radical polymerization with 5-fluorouracil (5-FU) as the template molecule using initiator of ammonium persulfate as adsorption system. MIPs were characterized by FTIR, X-ray diffraction, thermo-gravimetric analysis, (1)H NMR and SEM. The mechanism of graft copolymerization...
متن کاملMolecularly imprinted polymers in chemical and biological sensing.
In recent years the field of sensor technology has developed enormously, and biosensors in particular have attracted increased interest. This can be attributed to an extended demand for sensor devices for monitoring and control in biotechnology, the food industry, in the biomedical field, and in environmental analysis. Being highly sensitive and specific, biosensors provide an attractive altern...
متن کاملFabrication and Optimization of Molecularly Imprinted Nanofibers in Assessment of Occupational Exposure to 5-fluorouracil
Background and purpose: Cytotoxic drugs are a group of chemicals that raise concerns over the health of healthcare professionals. Therefore, accurate methods are needed to investigate the traces of these drugs. This study was done to fabricate and optimize molecularly imprinted membrane as a specific absorbent in assessment of occupational exposure to 5-fluorouracil. Materials and methods: 5-F...
متن کاملCitrinin selective molecularly imprinted polymers for SPE.
Molecularly imprinted polymers (MIPs) for citrinin (Cit) with 1-hydroxy-2-naphthoic acid (HNA) as mimic template were prepared and the molecularly imprinted SPE method was developed for the detection of Cit in rice with HPLC. The adsorption properties of HNA and Cit on the MIPs and nonimprinted polymers were investigated. It proved that MIPs showed higher selectivity adsorption to HNA and Cit t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecules
سال: 2007
ISSN: 1420-3049
DOI: 10.3390/12040805